•   Volume 3,Issue 1,2016

    Table of Contents

    Other Issues:       


    Cancer stem cells may contribute to the difficulty in treating cancer
      Sylvia Oghogho Iseghohi
      Published March 28, 2016
      2016,3(1):7-10 [Abstract]  [View PDF]

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    Revisiting vitamin C in cancer therapy: Is “C” for cure, or just wishful thinking?
      Fei Li, Lin Zhang and Shou-Ching Tang
      Published March 28, 2016
      2016,3(1):1-2 [Abstract]  [View PDF]


    Transition to resistance: An unexpected role of the EMT in cancer chemoresistance
      Jing Wang, Qiang Wei, Xin Wang, Shengli Tang, Hao Liu, Fugui Zhang, Maryam K. Mohammed, Jiayi Huang, Dan Guo, Minpeng Lu, Feng Liu, Jianxiang Liu, Chao Ma, Xue Hu, Rex C. Haydon and Tong-Chuan He
      Published March 28, 2016
      2016,3(1):3-6 [Abstract]  [View PDF]

    Review Article

    Wnt/β-catenin signaling plays an ever-expanding role in stem cell self-renewal, tumorigenesis and cancer chemoresistance
      Maryam K. Mohammed, Connie Shao, Jing Wang, Qiang Wei, Xin Wang, Zachary Collier, Shengli Tang, Hao Liu, Fugui Zhang, Jiayi Huang, Dan Guo, Minpeng Lu, Feng Liu, Jianxiang Liu, Chao Ma, Lewis L. Shi, Aravind Athiviraham, Tong-Chuan He and Michael J. Lee
      Published March 28, 2016
      2016,3(1):11-40 [Abstract]  [View PDF]
    Crosstalk of the Wnt/β-catenin pathway with other pathways in cancer cells
      Saint-Aaron L. Morris and Suyun Huang
      Published March 28, 2016
      2016,3(1):41-47 [Abstract]  [View PDF]
    Current understanding and dispute on the function of the Wnt signaling pathway effector TCF7L2 in hepatic gluconeogenesis
      Tianru Jin
      Published March 28, 2016
      2016,3(1):48-55 [Abstract]  [View PDF]
    Stem cells, growth factors and scaffolds in craniofacial regenerative medicine
      Viktor Tollemar, Zach J. Collier, Maryam K. Mohammed, Michael J. Lee, Guillermo A. Ameer and Russell R. Reid
      Published March 28, 2016
      2016,3(1):56-71 [Abstract]  [View PDF]
    Functional diversity of long non-coding RNAs in immune regulation
      Hua Geng and Xiao-Di Tan
      Published March 28, 2016
      2016,3(1):72-81 [Abstract]  [View PDF]

    Full Length Article

    Mitochondrial dysfunction activates the AMPK signaling and autophagy to promote cell survival
      Baozhong Zhao, Lei Qiang, Joy Joseph, Balaraman Kalyanaraman, Benoit Viollet and Yu-Ying He
      Published March 28, 2016
      2016,3(1):82-87 [Abstract]  [View PDF]
    Aberrant expression of Twist1 in diseased articular cartilage and a potential role in the modulation of osteoarthritis severity
      Rosa M. Guzzo, Farhang Alaee, David Paglia, Jason D. Gibson, Douglas Spicer and Hicham Drissi
      Published March 28, 2016
      2016,3(1):88-99 [Abstract]  [View PDF]