CRISPR clear? Dimeric Cas9-Fok1 nucleases improve genome-editing specificity

Editorial

Genes & Diseases,Volume 1, Issue 1,2014, Pages 6-7
CRISPR clear? Dimeric Cas9-Fok1 nucleases improve genome-editing specificity
Hongmei Zhang¹, Zhengjian Yan², Melissa Li³, Michael Peabody⁴, Tong-Chuan He⁵
1.Molecular Oncology Laboratory, The University of Chicago Medical Center, Chicago, IL 60637, USA;2.Molecular Oncology Laboratory, The University of Chicago Medical Center, Chicago, IL 60638, USA;3.Molecular Oncology Laboratory, The University of Chicago Medical Center, Chicago, IL 60639, USA;4.Molecular Oncology Laboratory, The University of Chicago Medical Center, Chicago, IL 60640, USA;5.Molecular Oncology Laboratory, The University of Chicago Medical Center, Chicago, IL 60641, USA

Abstract

Keywords

Cas9; CRISPR; Genome editing; sgRNA; TALENs; ZFNs